Chapter 10
Evans Syndrome: A Rare Case of Concurrent Autoimmune Haemolytic Anaemia and Immune Thrombocytopenia
- By Mithul V Mammen, Abhishek Anand, Amit Kumar, Ayush Mishra, Abhishek Suman - 26 Sep 2025
- Issues on Health Science, Volume: 1, Pages: 148 - 150
Abstract/Preface
Evans syndrome (ES) is a rare condition characterized by the concurrent or sequential development of autoimmune haemolytic anaemia (AIHA), immune thrombocytopenia (ITP), and/or immune neutropenia. It is marked by frequent relapses, a significant treatment burden, and increased risks of infection and thrombosis, substantially impacting survival. ES can be primary or secondary to conditions such as lymphoproliferative disorders, systemic autoimmune diseases, or primary immunodeficiencies. The syndrome severely affects survival and quality of life and is often severe and potentially fatal. Effective management requires prompt therapy, including anti-infectious and anti-thrombotic prophylaxis.